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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 650 Amish individuals; replicated in 847 European American ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.842 lower; p = 4 × 10−10.
How common The T allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 9, band 9q32 — between genes, 0.9 kb from ALAD.
What each result means
C/CNo copy of the version the research linked to Glycosphingolipids (d40:1) levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Glycosphingolipids (d40:1) levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Glycosphingolipids (d40:1) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2022 · PMID 35393526 · open access
Questions about rs112152257
What is rs112152257?
rs112152257 is a single position in the genome, in or near the near ALAD gene. Published research associates it with glycosphingolipids (d40:1) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs112152257 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs112152257 come from?
GWAS Catalog, Communications biology 2022, PMID:35393526. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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