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Who was studied 106,772 European ancestry cases, 239,773 European ancestry controls; replicated in 83,335 cases, 34,934 controls.
The effect
Each copy of the T allele carried 1.05 times the odds of Allergic disease (asthma, hay fever or eczema) (95% confidence interval 1.04-1.07); p = 3 × 10−18.
How common The T allele had a frequency of about 71% in the people studied.
Where it sits Chromosome 11, band 11q23.1 — between genes, 1.6 kb from LAYN.
What each result means
C/CNo copy of the version the research linked to Allergic disease (asthma, hay fever or eczema). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Allergic disease (asthma, hay fever or eczema). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Allergic disease (asthma, hay fever or eczema). That is the strongest link of the three results. A link in a study is not a diagnosis.
Human molecular genetics · 2019 · PMID 31361310 · open access
Questions about rs11213941
What is rs11213941?
rs11213941 is a single position in the genome, in or near the near LAYN gene. Published research associates it with allergic disease (asthma, hay fever or eczema). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11213941 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs11213941 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11213941 come from?
GWAS Catalog, Human molecular genetics 2019, PMID:31361310. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Allergic disease (asthma, hay fever or eczema) (rs11213941). MyGeneLog™. https://www.mygenelog.com/variants/rs11213941