Sensitive

Colorectal cancer

near POU2AF3 · rs11213825

Where this position leads

Condition: Colorectal Cancer

rs11213825 Condition: Colorectal Cancer Colorectal Cancer Condition rs11213825 rs11213825 near POU2AF3

What the study found

Who was studied 15,714 European ancestry cases, 621,182 European ancestry controls, 7,062 East Asian ancestry cases, 195,745 East Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 0.102 higher; p = 1 × 10−24.

Where it sits Chromosome 11, band 11q23.1 — between genes, 0.9 kb from POU2AF3.

What each result means

A/A Two copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
C/C No copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
Source

Questions about rs11213825

What is rs11213825?

rs11213825 is a single position in the genome, in or near the near POU2AF3 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11213825 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs11213825 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11213825 come from?

GWAS Catalog, Genome medicine 2024, PMID:38872215. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Colorectal cancer (rs11213825). MyGeneLog™. https://www.mygenelog.com/variants/rs11213825

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