A/APublished research associates this genotype with typical/baseline likelihood of Response to metformin in type 2 diabetes (glycemic) — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2010, PMID:21186350)
A/CPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Response to metformin in type 2 diabetes (glycemic). (GWAS Catalog, Nat Genet 2010, PMID:21186350)
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Response to metformin in type 2 diabetes (glycemic) compared to the general population. (GWAS Catalog, Nat Genet 2010, PMID:21186350)
rs11212617 is a single position in the genome, in or near the ATM gene. Published research associates it with response to metformin in type 2 diabetes (glycemic). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11212617 linked to?
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs11212617 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11212617 come from?
GWAS Catalog, Nat Genet 2010, PMID:21186350. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.