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Depressive symptoms

near LINC01360 · rs11210187

What the study found

Who was studied 1,067,913 European ancestry individuals; replicated in 228,033 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.00907 higher (95% confidence interval 0.0065-0.0116); p = 2 × 10−12.

How common The C allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 1, band 1p31.1 — between genes, 56.1 kb from LINC01360.

What each result means

C/C Two copies of the version the research linked to Depressive symptoms. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Depressive symptoms. That is a smaller link than two copies.
T/T No copy of the version the research linked to Depressive symptoms. This is the starting point the study compared everyone against.
Source

Questions about rs11210187

What is rs11210187?

rs11210187 is a single position in the genome, in or near the near LINC01360 gene. Published research associates it with depressive symptoms. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11210187 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11210187 come from?

GWAS Catalog, Nature genetics 2019, PMID:30643256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Depressive symptoms (rs11210187). MyGeneLog™. https://www.mygenelog.com/variants/rs11210187

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