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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,456 British ancestry obese children, 6,460 European ancestry control adults; replicated in up to 7,526 British ancestry obese individuals, at least 4,405 obese individuals, up to 20,720 British ancestry controls, 61,166 controls.
The effect
Each copy of the A allele carried 1.17 times the odds of Obesity (extreme) (95% confidence interval 1.13-1.21); p = 5 × 10−20.
How common The A allele had a frequency of about 72% in the people studied.
Where it sits Chromosome 1, band 1p31.1 — in an intron of LINC02796.
What each result means
A/ATwo copies of the version the research linked to Obesity (extreme). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Obesity (extreme). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Obesity (extreme). This is the starting point the study compared everyone against.
PLoS genetics · 2019 · PMID 30677029 · open access
Questions about rs11209947
What is rs11209947?
rs11209947 is a single position in the genome, in or near the NEGR1 gene. Published research associates it with obesity (extreme). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11209947 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11209947 come from?
GWAS Catalog, PLoS genetics 2019, PMID:30677029. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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