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C-reactive protein levels or triglyceride levels (pleiotropy)

LEPR · rs11208722

Where this position leads

Condition: C-Reactive Protein Levels

rs11208722 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs11208722 rs11208722 LEPR

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of C-reactive protein levels or triglyceride levels (pleiotropy) compared to the general population. (GWAS Catalog, BMC Genomics 2016, PMID:27286809)
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with C-reactive protein levels or triglyceride levels (pleiotropy). (GWAS Catalog, BMC Genomics 2016, PMID:27286809)
C/C Published research associates this genotype with typical/baseline likelihood of C-reactive protein levels or triglyceride levels (pleiotropy) — no copies of the reported risk allele. (GWAS Catalog, BMC Genomics 2016, PMID:27286809)

Source: GWAS Catalog, BMC Genomics 2016, PMID:27286809

Questions about rs11208722

What is rs11208722?

rs11208722 is a single position in the genome, in or near the LEPR gene. Published research associates it with c-reactive protein levels or triglyceride levels (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11208722 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs11208722 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11208722 come from?

GWAS Catalog, BMC Genomics 2016, PMID:27286809. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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