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Mean corpuscular volume

TRIM58 · rs11204538

Where this position leads

Condition: Blood Cell Counts

rs11204538 Condition: Blood Cell Counts Blood Cell Counts Condition rs11204538 rs11204538 TRIM58

What the study found

Who was studied 14,364 Japanese ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.091 lower (95% confidence interval 0.060-0.122); p = 2 × 10−8.

How common The C allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 1, band 1q44 — between genes, 2.8 kb from TRIM58.

What each result means

C/C Two copies of the version the research linked to Mean corpuscular volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean corpuscular volume. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean corpuscular volume. This is the starting point the study compared everyone against.
Source

Questions about rs11204538

What is rs11204538?

rs11204538 is a single position in the genome, in or near the TRIM58 gene. Published research associates it with mean corpuscular volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11204538 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs11204538 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11204538 come from?

GWAS Catalog, Nat Genet 2010, PMID:20139978. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular volume (rs11204538). MyGeneLog™. https://www.mygenelog.com/variants/rs11204538

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