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Lewy body pathology

LINC02929 · rs112017605

What the study found

Who was studied 158 European ancestry postmortem cases, 1,263 European ancestry postmortem controls.

The effect Each copy of the A allele carried 3.01 times the odds of Lewy body pathology (95% confidence interval 2.03-4.06); p = 5 × 10−10.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 10, band 10q21.2 — in an intron of LINC02929.

What each result means

A/A Two copies of the version the research linked to Lewy body pathology. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Lewy body pathology. That is a smaller link than two copies.
G/G No copy of the version the research linked to Lewy body pathology. This is the starting point the study compared everyone against.
Source

Questions about rs112017605

What is rs112017605?

rs112017605 is a single position in the genome, in or near the LINC02929 gene. Published research associates it with lewy body pathology. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs112017605 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs112017605 come from?

GWAS Catalog, Acta neuropathologica communications 2023, PMID:37700353. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lewy body pathology (rs112017605). MyGeneLog™. https://www.mygenelog.com/variants/rs112017605

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