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Late-onset myasthenia gravis

MHC_Class II · rs111945767

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Late-onset myasthenia gravis — no copies of the reported risk allele. (GWAS Catalog, Mol Med 2015, PMID:26562150)

C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Late-onset myasthenia gravis. (GWAS Catalog, Mol Med 2015, PMID:26562150)

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Late-onset myasthenia gravis compared to the general population. (GWAS Catalog, Mol Med 2015, PMID:26562150)

Source: GWAS Catalog, Mol Med 2015, PMID:26562150

Questions about rs111945767

What is rs111945767?

rs111945767 is a single position in the genome, in or near the MHC_Class II gene. Published research associates it with late-onset myasthenia gravis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs111945767 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs111945767 come from?

GWAS Catalog, Mol Med 2015, PMID:26562150. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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