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Who was studied 1,161 European ancestry cases, 4,683 European ancestry controls; replicated in 876 European ancestry cases, 1,890 European ancestry controls.
The effect
Each copy of the A allele carried 1.25 times the odds of Interstitial lung disease (95% confidence interval 1.15-1.35); p = 2 × 10−8.
How common The A allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 10, band 10q24.33 — in an intron of STN1.
What each result means
A/ATwo copies of the version the research linked to Interstitial lung disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Interstitial lung disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Interstitial lung disease. This is the starting point the study compared everyone against.
Nature genetics · 2013 · PMID 23583980 · open access
Questions about rs11191865
What is rs11191865?
rs11191865 is a single position in the genome, in or near the OBFC1 gene. Published research associates it with interstitial lung disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11191865 linked to?
On MyGeneLog this position is linked to Interstitial Lung Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs11191865 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11191865 come from?
GWAS Catalog, Nat Genet 2013, PMID:23583980. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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