Standard

Hypertension

NT5C2 · rs11191582

Where this position leads

Condition: Resistant Hypertension

rs11191582 Condition: Resistant Hypertension Resistant Hypertension Condition rs11191582 rs11191582 NT5C2

What the study found

Who was studied 13,413 Korean ancestry cases, 37,395 Korean ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−15.

Where it sits Chromosome 10, band 10q24.33 — in an intron of NT5C2.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hypertension compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hypertension.
G/G Published research associates this genotype with typical/baseline likelihood of Hypertension — no copies of the reported risk allele.
Source

Questions about rs11191582

What is rs11191582?

rs11191582 is a single position in the genome, in or near the NT5C2 gene. Published research associates it with hypertension. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11191582 linked to?

On MyGeneLog this position is linked to Resistant Hypertension. The research behind each link, and its sources, are set out on that condition page.

Does having rs11191582 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11191582 come from?

GWAS Catalog, International journal of molecular sciences 2022, PMID:36233190. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hypertension (rs11191582). MyGeneLog™. https://www.mygenelog.com/variants/rs11191582

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