Sensitive

Neuropsychiatric disorders

CNNM2 · rs11191499

What the study found

Who was studied 19,099 European ancestry attention deficit hyperactivity disorder cases, 18,381 European ancestry autism spectrum disorder cases, 20,352 European ancestry bipolar disorder cases, 170,756 European ancestry major depressive disorder cases, 33,640 European ancestry schizophrenia cases, 466,420 European ancestry controls.

The effect Each copy of the T allele shifted the measure 6.07 z score higher; p = 1 × 10−9.

Where it sits Chromosome 10, band 10q24.32 — in an intron of CNNM2.

What each result means

C/C No copy of the version the research linked to Neuropsychiatric disorders. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Neuropsychiatric disorders. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Neuropsychiatric disorders. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11191499

What is rs11191499?

rs11191499 is a single position in the genome, in or near the CNNM2 gene. Published research associates it with neuropsychiatric disorders. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11191499 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11191499 come from?

GWAS Catalog, Translational psychiatry 2021, PMID:33479212. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Neuropsychiatric disorders (rs11191499). MyGeneLog™. https://www.mygenelog.com/variants/rs11191499

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