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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,960 African American or Afro-Caribbean males.
The effect
Each copy of the A allele shifted the measure 0.183 higher (95% confidence interval 0.13-0.24); p = 4 × 10−11.
Where it sits Chromosome 17, band 17p13.1 — in an intron of SHBG.
What each result means
A/ATwo copies of the version the research linked to Sex hormone-binding globulin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Sex hormone-binding globulin levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Sex hormone-binding globulin levels. This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40316537 · open access
Questions about rs111901268
What is rs111901268?
rs111901268 is a single position in the genome, in or near the SHBG gene. Published research associates it with sex hormone-binding globulin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs111901268 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs111901268 come from?
GWAS Catalog, Nature communications 2025, PMID:40316537. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Sex hormone-binding globulin levels (rs111901268). MyGeneLog™. https://www.mygenelog.com/variants/rs111901268