Standard

Neuroticism

near LINC01947 · rs111871194

Where this position leads

Condition: Neuroticism

rs111871194 Condition: Neuroticism Neuroticism Condition rs111871194 rs111871194 near LINC019…

What the study found

Who was studied 523,783 European ancestry individuals; replicated in 59,206 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0147 lower (95% confidence interval 0.0098-0.0195); p = 4 × 10−9.

How common The C allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 5, band 5q34 — between genes, 222.9 kb from LINC01947.

What each result means

C/C Two copies of the version the research linked to Neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Neuroticism. That is a smaller link than two copies.
T/T No copy of the version the research linked to Neuroticism. This is the starting point the study compared everyone against.
Source

Questions about rs111871194

What is rs111871194?

rs111871194 is a single position in the genome, in or near the near LINC01947 gene. Published research associates it with neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs111871194 linked to?

On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.

Does having rs111871194 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs111871194 come from?

GWAS Catalog, Nature genetics 2019, PMID:30643256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Neuroticism (rs111871194). MyGeneLog™. https://www.mygenelog.com/variants/rs111871194

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