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IgA levels

SH2D4B · rs11186609

What the study found

Who was studied 1000 Metropolitan French ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.07 lower; p = 2 × 10−8.

Where it sits Chromosome 10, band 10q23.1 — between genes, 19.5 kb from RPS7P9.

What each result means

A/A No copy of the version the research linked to IgA levels. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to IgA levels. That is a smaller link than two copies.
C/C Two copies of the version the research linked to IgA levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11186609

What is rs11186609?

rs11186609 is a single position in the genome, in or near the SH2D4B gene. Published research associates it with iga levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11186609 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11186609 come from?

GWAS Catalog, Genome Med 2018, PMID:30053915. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

IgA levels (rs11186609). MyGeneLog™. https://www.mygenelog.com/variants/rs11186609

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