Standard

Age at menarche

PCGF5 · rs11186505

Where this position leads

Condition: Age at Menarche

rs11186505 Condition: Age at Menarche Age at Menarche Condition rs11186505 rs11186505 PCGF5

What the study found

Who was studied 371,060 European ancestry individuals, 67,029 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.01 higher (95% confidence interval 0.0061-0.0139); p = 2 × 10−8.

How common The A allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 10, band 10q23.32 — in an intron of PCGF5.

What each result means

A/A Two copies of the version the research linked to Age at menarche. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Age at menarche. That is a smaller link than two copies.
G/G No copy of the version the research linked to Age at menarche. This is the starting point the study compared everyone against.
Source

Questions about rs11186505

What is rs11186505?

rs11186505 is a single position in the genome, in or near the PCGF5 gene. Published research associates it with age at menarche. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11186505 linked to?

On MyGeneLog this position is linked to Age at Menarche. The research behind each link, and its sources, are set out on that condition page.

Does having rs11186505 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11186505 come from?

GWAS Catalog, Journal of human genetics 2024, PMID:39147824. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Age at menarche (rs11186505). MyGeneLog™. https://www.mygenelog.com/variants/rs11186505

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