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Male-pattern baldness

ARHGEF9 · rs111810219

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

What the study found

Who was studied 52,874 British ancestry males.

The effect Each copy of the A allele shifted the measure 0.207 lower; p = 1 × 10⁻¹⁴.

Where it sits Chromosome X, band Xq11.1 — in an intron of ARHGEF9.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Male-pattern baldness compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Male-pattern baldness.

G/G Published research associates this genotype with typical/baseline likelihood of Male-pattern baldness — no copies of the reported risk allele.

Source

Genetic prediction of male pattern baldness

Hagenaars SP, Hill WD, Harris SE, Ritchie SJ, Davies G, Liewald DC, Gale CR, Porteous DJ, Deary IJ, Marioni RE

PLoS genetics · 2017 · PMID 28196072 · open access

Questions about rs111810219

What is rs111810219?

rs111810219 is a single position in the genome, in or near the ARHGEF9 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs111810219 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs111810219 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs111810219 come from?

GWAS Catalog, PLoS Genet 2017, PMID:28196072. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Male-pattern baldness (rs111810219). MyGeneLog™. https://www.mygenelog.com/variants/rs111810219

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