0 26321218Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot3Amazon2Apple1China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others18Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 315,133 European ancestry individuals, 74,970 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0135 higher (95% confidence interval 0.0092-0.0178); p = 5 × 10−10.
Where it sits Chromosome 12, band 12q15 — in an intron of PTPRR.
What each result means
A/ATwo copies of the version the research linked to HDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to HDL cholesterol. That is a smaller link than two copies.
G/GNo copy of the version the research linked to HDL cholesterol. This is the starting point the study compared everyone against.
rs11178376 is a single position in the genome, in or near the PTPRR gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11178376 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs11178376 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11178376 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 26321218Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot3Amazon2Apple1China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others18Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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