Sensitive

Parkinson's disease

near MUC19 · rs11177328

Where this position leads

Condition: Parkinson's Disease

rs11177328 Condition: Parkinson's Disease Parkinson's Disease Condition rs11177328 rs11177328 near MUC19

What the study found

Who was studied 57,893 European ancestry cases, 1,505,102 European ancestry controls, 7,046 East Asian ancestry cases, 176,756 East Asian ancestry controls, 2,440 Hispanic or Latin American cases, 582,220 Hispanic or Latin American controls, 288 African ancestry cases, 193,985 African ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 3 × 10−11.

Where it sits Chromosome 12, band 12q12 — between genes, 13.2 kb from MUC19.

What each result means

A/A Two copies of the version the research linked to Parkinson's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Parkinson's disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Parkinson's disease. This is the starting point the study compared everyone against.
Source

Questions about rs11177328

What is rs11177328?

rs11177328 is a single position in the genome, in or near the near MUC19 gene. Published research associates it with parkinson's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11177328 linked to?

On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs11177328 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11177328 come from?

GWAS Catalog, Nature genetics 2024, PMID:38155330. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Parkinson's disease (rs11177328). MyGeneLog™. https://www.mygenelog.com/variants/rs11177328

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