Sensitive

Osteoarthritis

GNL3 · rs11177

Where this position leads

Condition: Knee Osteoarthritis

rs11177 Condition: Knee Osteoarthritis Knee Osteoarthritis Condition rs11177 rs11177 GNL3

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Osteoarthritis compared to the general population. (GWAS Catalog, Lancet 2012, PMID:22763110)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Osteoarthritis. (GWAS Catalog, Lancet 2012, PMID:22763110)
G/G Published research associates this genotype with typical/baseline likelihood of Osteoarthritis — no copies of the reported risk allele. (GWAS Catalog, Lancet 2012, PMID:22763110)

Source: GWAS Catalog, Lancet 2012, PMID:22763110

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs11177

What is rs11177?

rs11177 is a single position in the genome, in or near the GNL3 gene. Published research associates it with osteoarthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11177 linked to?

On MyGeneLog this position is linked to Knee Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs11177?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs11177 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11177 come from?

GWAS Catalog, Lancet 2012, PMID:22763110. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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