Standard

Creatinine levels

TDRD12 · rs111714445

Where this position leads

Conditions: Kidney Function, Gout

rs111714445 Condition: Kidney Function Kidney Function Condition Condition: Gout Gout Condition rs111714445 rs111714445 TDRD12

What the study found

Who was studied 342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0709 lower (95% confidence interval 0.056-0.086); p = 2 × 10−21.

Where it sits Chromosome 19, band 19q13.11 — in an intron of TDRD12.

What each result means

C/C No copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs111714445

What is rs111714445?

rs111714445 is a single position in the genome, in or near the TDRD12 gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs111714445 linked to?

On MyGeneLog this position is linked to Kidney Function, Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs111714445 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs111714445 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Creatinine levels (rs111714445). MyGeneLog™. https://www.mygenelog.com/variants/rs111714445

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