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Free cholesterol levels

CHLSN · rs111705570

What the study found

Who was studied 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0447 higher (95% confidence interval 0.034-0.056); p = 2 × 10−15.

How common The A allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 7, band 7p22.3 — in an intron of CHLSN.

What each result means

A/A Two copies of the version the research linked to Free cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Free cholesterol levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Free cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs111705570

What is rs111705570?

rs111705570 is a single position in the genome, in or near the CHLSN gene. Published research associates it with free cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs111705570 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs111705570 come from?

GWAS Catalog, Nature 2024, PMID:38448586. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Free cholesterol levels (rs111705570). MyGeneLog™. https://www.mygenelog.com/variants/rs111705570

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