Who was studied 22,049 European ancestry cases, 332,368 European ancestry controls, 4,768 East Asian ancestry cases, 166,052 East Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0568 higher (95% confidence interval 0.038-0.075); p = 2 × 10−9.
Where it sits Chromosome 12, band 12q13.12 — in an intron of ATF1.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Colon polyp — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Colon polyp.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Colon polyp compared to the general population.
rs11169562 is a single position in the genome, in or near the ATF1 gene. Published research associates it with colon polyp. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11169562 linked to?
On MyGeneLog this position is linked to Colon Polyp. The research behind each link, and its sources, are set out on that condition page.
Does having rs11169562 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11169562 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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