C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Inflammatory bowel disease compared to the general population. (GWAS Catalog, Nature 2012, PMID:23128233)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Inflammatory bowel disease. (GWAS Catalog, Nature 2012, PMID:23128233)
T/TPublished research associates this genotype with typical/baseline likelihood of Inflammatory bowel disease — no copies of the reported risk allele. (GWAS Catalog, Nature 2012, PMID:23128233)
Source: GWAS Catalog, Nature 2012, PMID:23128233
Questions about rs11168249
What is rs11168249?
rs11168249 is a single position in the genome, in or near the VDR gene. Published research associates it with inflammatory bowel disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11168249 linked to?
On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs11168249 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11168249 come from?
GWAS Catalog, Nature 2012, PMID:23128233. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.