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FGFR2 protein levels

NFATC3 · rs111632263

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0623 higher (95% confidence interval 0.046-0.079); p = 4 × 10−15.

How common The A allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 16, band 16q22.1 — in an intron of NFATC3.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of FGFR2 protein levels compared to the general population.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with FGFR2 protein levels.
T/T Published research associates this genotype with typical/baseline likelihood of FGFR2 protein levels — no copies of the reported risk allele.
Source

Questions about rs111632263

What is rs111632263?

rs111632263 is a single position in the genome, in or near the NFATC3 gene. Published research associates it with fgfr2 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs111632263 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs111632263 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

FGFR2 protein levels (rs111632263). MyGeneLog™. https://www.mygenelog.com/variants/rs111632263

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