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Chronotype

PIGK · rs11162296

Where this position leads

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Chronotype — no copies of the reported risk allele.

C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Chronotype.

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Chronotype compared to the general population.

Source

Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci

Jones SE, Tyrrell J, Wood AR, Beaumont RN, Ruth KS, Tuke MA, Yaghootkar H, Hu Y, Teder-Laving M, Hayward C, Roenneberg T, Wilson JF

and 15 more — show all

Del Greco F, Hicks AA, Shin C, Yun CH, Lee SK, Metspalu A, Byrne EM, Gehrman PR, Tiemeier H, Allebrandt KV, Freathy RM, Murray A, Hinds DA, Frayling TM, Weedon MN

PLoS genetics · 2016 · PMID 27494321 · open access

Questions about rs11162296

What is rs11162296?

rs11162296 is a single position in the genome, in or near the PIGK gene. Published research associates it with chronotype. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11162296 linked to?

On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.

Does having rs11162296 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11162296 come from?

GWAS Catalog, PLoS Genet 2016, PMID:27494321. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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