Standard
Preterm birth (maternal effect) (maternal pre-pregnancy BMI interaction)
COL24A1 · rs11161721
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Preterm birth (maternal effect) (maternal pre-pregnancy BMI interaction) compared to the general population.
A/C
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Preterm birth (maternal effect) (maternal pre-pregnancy BMI interaction).
C/C
Published research associates this genotype with typical/baseline likelihood of Preterm birth (maternal effect) (maternal pre-pregnancy BMI interaction) — no copies of the reported risk allele.
Source
Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth
Hong X,
Hao K,
Ji H,
Peng S,
Sherwood B,
Di Narzo A,
Tsai HJ,
Liu X,
Burd I,
Wang G,
Ji Y,
Caruso D
and 12 more — show all
Mao G,
Bartell TR,
Zhang Z,
Pearson C,
Heffner L,
Cerda S,
Beaty TH,
Fallin MD,
Lee-Parritz A,
Zuckerman B,
Weeks DE,
Wang X
Nature communications · 2017 · PMID 28598419 · open access
Questions about rs11161721
What is rs11161721?
rs11161721 is a single position in the genome, in or near the COL24A1 gene. Published research associates it with preterm birth (maternal effect) (maternal pre-pregnancy bmi interaction). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11161721 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11161721 come from?
GWAS Catalog, Nat Commun 2017, PMID:28598419. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants