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IgG glycosylation patterns

FUT8 · rs11158592

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of IgG glycosylation patterns — no copies of the reported risk allele. (GWAS Catalog, Front Immunol 2018, PMID:29535710)

G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with IgG glycosylation patterns. (GWAS Catalog, Front Immunol 2018, PMID:29535710)

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of IgG glycosylation patterns compared to the general population. (GWAS Catalog, Front Immunol 2018, PMID:29535710)

Source: GWAS Catalog, Front Immunol 2018, PMID:29535710

Questions about rs11158592

What is rs11158592?

rs11158592 is a single position in the genome, in or near the FUT8 gene. Published research associates it with igg glycosylation patterns. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11158592 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11158592 come from?

GWAS Catalog, Front Immunol 2018, PMID:29535710. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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