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QT interval

C6orf204 · rs11153730

Where this position leads

Condition: QT Interval and Drug-Induced Long QT

rs11153730 Condition: QT Interval and Drug-Induced Long QT QT Interval and Drug-Induced Long QT Condition rs11153730 rs11153730 C6orf204

What the study found

Who was studied 3,558 European ancestry individuals; replicated in 29,527 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.09 higher; p = 2 × 10−29.

How common The C allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 6, band 6q22.31 — between genes, 28.7 kb from SLC35F1.

What each result means

C/C Two copies of the version the research linked to QT interval. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to QT interval. That is a smaller link than two copies.
T/T No copy of the version the research linked to QT interval. This is the starting point the study compared everyone against.
Source

Questions about rs11153730

What is rs11153730?

rs11153730 is a single position in the genome, in or near the C6orf204 gene. Published research associates it with qt interval. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11153730 linked to?

On MyGeneLog this position is linked to QT Interval and Drug-Induced Long QT. The research behind each link, and its sources, are set out on that condition page.

Does having rs11153730 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11153730 come from?

GWAS Catalog, PLoS One 2009, PMID:19587794. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

QT interval (rs11153730). MyGeneLog™. https://www.mygenelog.com/variants/rs11153730

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