0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
The effect
Each copy of the G allele shifted the measure 0.833 lower (95% confidence interval 0.53-1.13); p = 5 × 10−8.
Where it sits Chromosome 2, band 2q24.3 — in an intron of SCN2A.
What each result means
A/ANo copy of the version the research linked to Rate of cognitive decline in Alzheimer's disease. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Rate of cognitive decline in Alzheimer's disease. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Rate of cognitive decline in Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2020 · PMID 32573913
Questions about rs111535588
What is rs111535588?
rs111535588 is a single position in the genome, in or near the SCN2A gene. Published research associates it with rate of cognitive decline in alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs111535588 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs111535588 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs111535588 come from?
GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2020, PMID:32573913. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Rate of cognitive decline in Alzheimer's disease (rs111535588). MyGeneLog™. https://www.mygenelog.com/variants/rs111535588