Standard

Apolipoprotein B levels

HS1BP3 · rs111508381

What the study found

Who was studied 340,860 European ancestry individuals, 5,962 African ancestry individuals, 7,275 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0437 lower (95% confidence interval 0.029-0.058); p = 2 × 10−9.

Where it sits Chromosome 2, band 2p24.1 — in an intron of HS1BP3.

What each result means

A/A Two copies of the version the research linked to Apolipoprotein B levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Apolipoprotein B levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Apolipoprotein B levels. This is the starting point the study compared everyone against.
Source

Questions about rs111508381

What is rs111508381?

rs111508381 is a single position in the genome, in or near the HS1BP3 gene. Published research associates it with apolipoprotein b levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs111508381 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs111508381 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Apolipoprotein B levels (rs111508381). MyGeneLog™. https://www.mygenelog.com/variants/rs111508381

← See all variants