0 1612310Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others10Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 134,070 European ancestry individuals, 143,658 East Asian ancestry individuals, 26,344 Hispanic or Latino ancestry individuals, 8,224 African American individuals.
The effect
Each copy of the T allele shifted the measure 0.501 ml/min/1.73m2 lower (95% confidence interval 0.34-0.66); p = 5 × 10−30.
How common The T allele had a frequency of about 32% in the people studied.
Where it sits Chromosome 4, band 4q21.1 — in an intron of SHROOM3.
What each result means
C/CNo copy of the version the research linked to Estimated glomerular filtration rate. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Estimated glomerular filtration rate. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Estimated glomerular filtration rate. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2019 · PMID 30604766 · open access
Questions about rs111449836
What is rs111449836?
rs111449836 is a single position in the genome, in or near the SHROOM3 gene. Published research associates it with estimated glomerular filtration rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs111449836 linked to?
On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.
Does having rs111449836 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs111449836 come from?
GWAS Catalog, Nat Commun 2019, PMID:30604766. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1612310Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others10Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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