Standard

Magnesium levels

TRPM6 · rs11144134

Where this position leads

Supplement: Magnesium

rs11144134 Supplement: Magnesium Magnesium Supplement rs11144134 rs11144134 TRPM6

What the study found

Who was studied 15,366 European ancestry individuals; replicated in 8,463 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.01 mmol/L lower (95% confidence interval 0.009-0.013); p = 8 × 10−15.

How common The T allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 9, band 9q21.13 — in an intron of TRPM6.

What each result means

C/C No copy of the version the research linked to Magnesium levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Magnesium levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Magnesium levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs11144134

What is rs11144134?

rs11144134 is a single position in the genome, in or near the TRPM6 gene. Published research associates it with magnesium levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs11144134?

Subjects that appear in the title or abstract of the same papers as this rsID include kidneys (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs11144134 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11144134 come from?

GWAS Catalog, PLoS Genet 2010, PMID:20700443. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Magnesium levels (rs11144134). MyGeneLog™. https://www.mygenelog.com/variants/rs11144134

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