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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 49,327 East Asian ancestry cases, 129,399 East Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0546 higher (95% confidence interval 0.037-0.072); p = 2 × 10−9.
How common The T allele had a frequency of about 29% in the people studied.
Where it sits Chromosome 6, band 6p21.1 — between genes, 0.5 kb from SLC22A7.
What each result means
C/CNo copy of the version the research linked to Medication use (calcium channel blockers). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Medication use (calcium channel blockers). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Medication use (calcium channel blockers). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs1114357 is a single position in the genome, in or near the near SLC22A7 gene. Published research associates it with medication use (calcium channel blockers). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1114357 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1114357 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Medication use (calcium channel blockers) (rs1114357). MyGeneLog™. https://www.mygenelog.com/variants/rs1114357