0 271822113Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot8Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others13Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 322,141 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 6.22 z score lower; p = 5 × 10−10.
Where it sits Chromosome 17, band 17q21.31 — in an intron of PLEKHM1.
What each result means
A/ATwo copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
rs111423688 is a single position in the genome, in or near the PLEKHM1 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs111423688 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs111423688 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs111423688 come from?
GWAS Catalog, HGG advances 2025, PMID:39663699. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 271822113Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot8Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others13Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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