0 22422212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI4Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others12Total22Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 118,811 European ancestry cases, 327,427 European ancestry controls, 127,552 cases, 233,763 controls; replicated in 414,055 European ancestry cases, 892,299 European ancestry controls.
The effect
Each copy of the C allele carried 1.03 times the odds of Depression (95% confidence interval 1.02-1.03); p = 2 × 10−30.
How common The C allele had a frequency of about 53% in the people studied.
Where it sits Chromosome 5, band 5q34 — in an intron of LINC03000.
What each result means
A/ANo copy of the version the research linked to Depression. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Depression. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Depression. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs11135349 is a single position in the genome, in or near the LINC03000 gene. Published research associates it with depression. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11135349 linked to?
On MyGeneLog this position is linked to Endometriosis and Depression: Shared Genetics. The research behind each link, and its sources, are set out on that condition page.
Does having rs11135349 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11135349 come from?
GWAS Catalog, Nature neuroscience 2019, PMID:30718901. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22422212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI4Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others12Total22Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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