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Volume of left cortical nucleus

near RPL22P13 · rs11133310

What the study found

Who was studied 35,474 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0438 higher (95% confidence interval 0.03-0.058); p = 9 × 10−10.

How common The G allele had a frequency of about 53% in the people studied.

Where it sits Chromosome 4, band 4q12 — between genes, 46.9 kb from RPL22P13.

What each result means

A/A No copy of the version the research linked to Volume of left cortical nucleus. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Volume of left cortical nucleus. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Volume of left cortical nucleus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11133310

What is rs11133310?

rs11133310 is a single position in the genome, in or near the near RPL22P13 gene. Published research associates it with volume of left cortical nucleus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11133310 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11133310 come from?

GWAS Catalog, Nature genetics 2025, PMID:40097784. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Volume of left cortical nucleus (rs11133310). MyGeneLog™. https://www.mygenelog.com/variants/rs11133310

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