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IL17RB protein levels

near CABYRP1 · rs11130391

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.189 higher (95% confidence interval 0.14-0.24); p = 3 × 10−20.

How common The C allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 3, band 3p21.1 — between genes, 31.1 kb from CABYRP1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of IL17RB protein levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with IL17RB protein levels.
T/T Published research associates this genotype with typical/baseline likelihood of IL17RB protein levels — no copies of the reported risk allele.
Source

Questions about rs11130391

What is rs11130391?

rs11130391 is a single position in the genome, in or near the near CABYRP1 gene. Published research associates it with il17rb protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11130391 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11130391 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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IL17RB protein levels (rs11130391). MyGeneLog™. https://www.mygenelog.com/variants/rs11130391

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