HHEX · rs1112718
Where this position leads
Condition: Multiple Sclerosis
What the study found
Who was studied 14,802 European and unknown ancestry cases, 26,703 European and unknown ancestry controls; replicated in 32,627 European and unknown ancestry cases, 41,672 European and unknown ancestry controls.
The effect Each copy of the A allele carried 1.09 times the odds of Multiple sclerosis; p = 2 × 10−17.
Where it sits Chromosome 10, band 10q23.33 — between genes, 8.7 kb from Y_RNA.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs1112718 is a single position in the genome, in or near the HHEX gene. Published research associates it with multiple sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Multiple Sclerosis. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Science 2019, PMID:31604244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Multiple sclerosis (rs1112718). MyGeneLog™. https://www.mygenelog.com/variants/rs1112718