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Vertical cup-disc ratio

LINC01705 · rs11118873

What the study found

Who was studied 65,680 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.00374 higher (95% confidence interval 0.0024-0.0051); p = 4 × 10−10.

How common The A allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 1, band 1q41 — in an intron of LINC01705.

What each result means

A/A Two copies of the version the research linked to Vertical cup-disc ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Vertical cup-disc ratio. That is a smaller link than two copies.
G/G No copy of the version the research linked to Vertical cup-disc ratio. This is the starting point the study compared everyone against.
Source

Questions about rs11118873

What is rs11118873?

rs11118873 is a single position in the genome, in or near the LINC01705 gene. Published research associates it with vertical cup-disc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11118873 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11118873 come from?

GWAS Catalog, American journal of human genetics 2021, PMID:34077760. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Vertical cup-disc ratio (rs11118873). MyGeneLog™. https://www.mygenelog.com/variants/rs11118873

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