CASC18 · rs11112709
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,704 European ancestry cases, 272,842 European ancestry controls; replicated in 955 European ancestry cases, 90,893 European ancestry controls.
The effect The reported allele is T; the catalogue records no effect size ; p = 4 × 10−10.
How common The T allele had a frequency of about 16% in the people studied.
Where it sits Chromosome 12, band 12q23.3 — in an intron of CASC18.
rs11112709 is a single position in the genome, in or near the CASC18 gene. Published research associates it with ventral hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Hernia : the journal of hernias and abdominal wall surgery 2022, PMID:34382107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Ventral hernia (rs11112709). MyGeneLog™. https://www.mygenelog.com/variants/rs11112709