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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 27,302 European ancestry individuals; replicated in 11,264 European ancestry individuals.
The effect
The reported allele is G; the catalogue records no effect size
; p = 2 × 10−21.
Where it sits Chromosome 12, band 12q23.2 — in an intron of IGF1.
What each result means
A/ANo copy of the version the research linked to Cerebellar grey matter morphology (MOSTest). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Cerebellar grey matter morphology (MOSTest). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Cerebellar grey matter morphology (MOSTest). That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2026 · PMID 41703085 · open access
Questions about rs11111278
What is rs11111278?
rs11111278 is a single position in the genome, in or near the IGF1 gene. Published research associates it with cerebellar grey matter morphology (mostest). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11111278 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11111278 come from?
GWAS Catalog, Communications biology 2026, PMID:41703085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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