Sensitive

Colorectal cancer

PGAM1P5 · rs11108174

Where this position leads

Condition: Colorectal Cancer

rs11108174 Condition: Colorectal Cancer Colorectal Cancer Condition rs11108174 rs11108174 PGAM1P5

What the study found

Who was studied 15,714 European ancestry cases, 621,182 European ancestry controls, 7,062 East Asian ancestry cases, 195,745 East Asian ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0546 higher; p = 1 × 10−10.

Where it sits Chromosome 12, band 12q22 — in an intron of PGAM1P5.

What each result means

C/C No copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11108174

What is rs11108174?

rs11108174 is a single position in the genome, in or near the PGAM1P5 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11108174 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs11108174 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11108174 come from?

GWAS Catalog, Genome medicine 2024, PMID:38872215. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Colorectal cancer (rs11108174). MyGeneLog™. https://www.mygenelog.com/variants/rs11108174

← See all variants