A/APublished research associates this genotype with typical/baseline likelihood of Free thyroxine concentration — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Free thyroxine concentration.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Free thyroxine concentration compared to the general population.
Nature communications · 2015 · PMID 25743335 · open access
Questions about rs11103377
What is rs11103377?
rs11103377 is a single position in the genome, in or near the LHX3 gene. Published research associates it with free thyroxine concentration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11103377 linked to?
On MyGeneLog this position is linked to Thyroid Stimulating Hormone (TSH) Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs11103377 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11103377 come from?
GWAS Catalog, Nat Commun 2015, PMID:25743335. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.