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ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 levels

BST1 · rs1110258

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.366 higher (95% confidence interval 0.3-0.43); p = 3 × 10−30.

How common The G allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 4, band 4p15.32 — in an intron of BST1.

What each result means

A/A No copy of the version the research linked to ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1110258

What is rs1110258?

rs1110258 is a single position in the genome, in or near the BST1 gene. Published research associates it with adp-ribosyl cyclase/cyclic adp-ribose hydrolase 2 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1110258 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1110258 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 levels (rs1110258). MyGeneLog™. https://www.mygenelog.com/variants/rs1110258

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