0 473256223222Reads by AI crawlersClaude3ChatGPT2Google · Gemini5Perplexity0Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 5,201 European ancestry cases, 9,066 European ancestry controls.
The effect
Each copy of the C allele carried 1.24 times the odds of Systemic lupus erythematosus; p = 1 × 10−13.
Where it sits Chromosome 19, band 19p13.2 — in an intron of TYK2.
What each result means
C/CTwo copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
Nature genetics · 2015 · PMID 26502338 · open access
Questions about rs11085727
What is rs11085727?
rs11085727 is a single position in the genome, in or near the TYK2 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11085727 linked to?
On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.
Does having rs11085727 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11085727 come from?
GWAS Catalog, Nat Genet 2015, PMID:26502338. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 473256223222Reads by AI crawlersClaude3ChatGPT2Google · Gemini5Perplexity0Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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