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Standard

Height

near RPL23AP75 · rs11078945

Strength of the evidence

2 / 4

Its strongest genetic-study result is p = 10−32, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 455,180 Hispanic or Latin American individuals.

The effect Each copy of the T allele shifted the measure 0.0257 higher (95% confidence interval 0.021-0.03); p = 7 × 10−33.

How common The T allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 17, band 17q21.2 — between genes, 1 kb from RPL23AP75.

How common each version is

GT
Korean KRGDB
G 46.9% · T 53.1%
Korean Korea4K
G 45.4% · T 54.6%
Korean Korea1K
G 45.2% · T 54.8%
Japanese ToMMo
G 43.0% · T 57.0%
Vietnamese
G 50.5% · T 49.5%
World gnomAD
G 49.1% · T 50.9%
World 1000 Genomes
G 53.2% · T 46.8%
World TOPMed
G 50.3% · T 49.7%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study.

What each result means

G/G No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Height. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Quoting this page

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Height (rs11078945). MyGeneLog™. https://www.mygenelog.com/variants/rs11078945

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