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Who was studied 5,571 Chinese ancestry individuals; replicated in 2,981 Chinese ancestry individuals.
The effect
Each copy of the T allele shifted the measure 7.39 z score lower; p = 1 × 10−13.
How common The T allele had a frequency of about 50% in the people studied.
Where it sits Chromosome 17, band 17p13.3 — in an intron of CRK.
What each result means
A/ANo copy of the version the research linked to Intraocular pressure. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Intraocular pressure. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Intraocular pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science China. Life sciences · 2019 · PMID 30591961
Questions about rs11078446
What is rs11078446?
rs11078446 is a single position in the genome, in or near the CRK gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11078446 linked to?
On MyGeneLog this position is linked to Intraocular Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs11078446 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11078446 come from?
GWAS Catalog, Science China. Life sciences 2019, PMID:30591961. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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