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Who was studied 28,283 European ancestry individuals; replicated in 22,054 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 5.16 umol/l lower (95% confidence interval 3.65-6.67); p = 2 × 10−11.
How common The T allele had a frequency of about 23% in the people studied.
Where it sits Chromosome 12, band 12q13.3 — in an intron of R3HDM2.
What each result means
C/CNo copy of the version the research linked to Urate levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Urate levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Urate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs1106766
What is rs1106766?
rs1106766 is a single position in the genome, in or near the INHBC gene. Published research associates it with urate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1106766 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs1106766?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs1106766 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1106766 come from?
GWAS Catalog, Circ Cardiovasc Genet 2010, PMID:20884846. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 4532124222225Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity2Meta AI4Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total45Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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